Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456679 | 0.80 | CYP3A4 (0.45) | ALDH1A1MAPTMAPK1HTTPOLB | |
| SCHEMBL1137068 | 0.76 | KDM4E (0.54) | ATMDDB1CRBNALDH1A1MAPT | |
| SCHEMBL13575331 | 0.75 | ATM (0.47) | ATMCOMTDDB1CRBNALDH1A1 | |
| SCHEMBL15803829 | 0.75 | SMN1; SMN2 (0.50) | ATMCOMTDDB1CRBNALDH1A1 | |
| SCHEMBL747392 | 0.75 | NOTUM (0.47) | ATMCOMTDDB1CRBNALDH1A1 | |
| SCHEMBL3974215 | 0.73 | MAPT (0.49) | ATMDDB1CRBNALDH1A1MAPT | |
| SCHEMBL1396731 | 0.73 | MAPK1 (0.58) | ATMALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL12971416 | 0.73 | ATM (0.48) | ATMCOMTDDB1CRBNALDH1A1 | |
| SCHEMBL16256868 | 0.72 | ATM (0.58) | ATMDDB1CRBNALDH1A1MAPT | |
| SCHEMBL3963253 | 0.72 | ATM (0.44) | ATMCOMTDDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034836-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |