SCHEMBL747392

SCHEMBL747392

Cc1cccn(-c2ccccc2)c1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.47
ATM Q13315 1/20 0.47
COMT P21964 1/20 0.46
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 3/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 2/20 0.46
BLM P54132 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KAT2B Q92831 1/20 0.44
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
MAPT P10636 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MCL1 Q07820 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
EP300 Q09472 1/20 0.41
KAT8 Q9H7Z6 1/20 0.41
MITF O75030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6142617 0.88 MAPT (0.43) NOTUMATMCOMTALDH1A1KDM4E
SCHEMBL14018033 0.82 PTGS2 (0.45) ALDH1A1KDM4EMAPTLMNAPTGS1
SCHEMBL13153504 0.82 FAAH (0.38) NOTUMALDH1A1HPGDMAPTMEN1
SCHEMBL9109139 0.82 MMP8 (0.42) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL3834300 0.82 ALDH1A1 (0.40) ATMALDH1A1KDM4EHSD17B10MAPT
SCHEMBL9292198 0.81 HSP90AA1 (0.49) NOTUMALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1344141 0.80 TRPV1 (0.43) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL31456729 0.80 CYP2A6 (0.53) ALDH1A1HSD17B10KAT2BMAPTEP300
SCHEMBL4282578 0.78 HTT (0.51) NOTUMCYP1A2MAPTMEN1KMT2A
SCHEMBL30613481 0.78 COMT (0.49) NOTUMATMCOMTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514348-A2 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) Noetix Pharma LLC (US) 2025-03-05 EP claimed
US-20240299698-A1 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) NOETIX PHARMA LLC 2024-09-12 US claimed
WO-2023211684-A2 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) NOETIX PHARMA LLC (US) 2023-11-02 WO claimed
US-20230293519-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS PLIANT THERAPEUTICS INC (US) 2023-09-21 US claimed
CN-108883072-A Granular preparation of 5-methyl-1-phenyl-2- (1H) -pyridone and preparation method thereof 霍夫曼-拉罗奇有限公司 2018-11-23 CN claimed
US-20180243277-A1 GRANULATE FORMULATION OF 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE AND METHOD OF MAKING THE SAME F. HOFFMANN-LA ROCHE AG (CH) 2018-08-30 US claimed
US-8753679-B2 Capsule formulation of pirfenidone and pharmaceutically acceptable excipients INTERMUNE, INC. (US) 2014-06-17 US claimed
US-8287900-B2 Medicated patch comprising 5-methyl-1-phenyl-2-(1H)-pyridone LEAD CHEMICAL CO., LTD. (JP) 2012-10-16 US claimed
EP-2431025-A1 Capsule formulation of pirfenidone and pharmaceutically acceptable excipients Intermune, Inc. (US) 2012-03-21 EP claimed
US-7605173-B2 Pharmaceutical liquid composition containing pyridone derivative KDL, INC. (JP) 2009-10-20 US claimed
EP-1539155-B1 STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION MEPHA AG (CH) 2008-04-02 EP claimed
EP-0866656-B1 USE OF N-SUBSTITUTED PYRIDONES AS TUMOR NECROSIS FACTOR ALPHA INHIBITORS MARGOLIN SOLOMON B (US) 2007-04-25 EP claimed
US-20060039931-A1 Stable cream preparations of phenyl-pyridone compounds for topical application MEPHA AG (CH) 2006-02-23 US claimed
EP-1138329-B1 Composition containing 5-Methyl-1-phenyl-2-(1 H)-pyridone for reparation and prevention of fibrotic lesions YAMAUCHI SHITOTOMO (JP) 2004-06-02 EP claimed
EP-1069898-B1 TOPICAL ANTISEPTIC COMPOSITIONS AND METHODS MARGOLIN SOLOMON B (US) 2004-05-12 EP claimed
EP-0813409-B1 TREATMENT OF CYTOKINE GROWTH FACTOR CAUSED DISORDERS MARGOLIN SOLOMON B (US) 2004-05-06 EP claimed
EP-0702551-B1 COMPOSITIONS AND METHODS FOR REPARATION AND PREVENTION OF FIBROTIC LESIONS MARGOLIN SOLOMON B (US) 2002-09-25 EP claimed
EP-1138329-A2 Composition containing 5-Methyl-1-phenyl-2-(1 H)-pyridone for reparation and prevention of fibrotic lesions Yamauchi, Shitotomo (JP) 2001-10-04 EP claimed
US-5962478-A ADMINISTERING A N-SUBSTITUTED 2(1H)PYRIDONE INTERMUNE, INC. 1999-10-05 US claimed
US-20250367178-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC (US) 2025-12-04 US disclosed
US-20250213539-A1 METHODS OF USING A PHARMACEUTICAL COMPOSITION CONTAINING PIRFENIDONE IN SUSTAINED-RELEASE TABLET FORM EXCALIBUR PHARMACEUTICALS, INC. (US) 2025-07-03 US disclosed
EP-4551204-A2 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS Pliant Therapeutics, Inc. (US) 2025-05-14 EP disclosed
US-20250114376-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. 2025-04-10 US disclosed
EP-4514348-A2 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) Noetix Pharma LLC (US) 2025-03-05 EP disclosed
US-12226407-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2025-02-18 US disclosed
EP-4491180-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF Avalyn Pharma Inc. (US) 2025-01-15 EP disclosed
US-20240299698-A1 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) NOETIX PHARMA LLC 2024-09-12 US disclosed
US-12083106-B2 Methods of using a pharmaceutical composition containing pirfenidone in sustained-release tablet form EXCALIBUR PHARMACEUTICALS, INC. (US) 2024-09-10 US disclosed
WO-2024155965-A2 BIOMARKERS FOR USE IN INTEGRIN INHIBITOR THERAPY PLIANT THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
EP-3091976-B1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC (US) 2024-07-24 EP disclosed
US-12023342-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2024-07-02 US disclosed
US-20240122930-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS PLIANT THERAPEUTICS, INC. 2024-04-18 US disclosed
CN-111372945-B Treatment of idiopathic pulmonary interstitial fibrosis based on oxyntomodulin analog GLP-1R/GCGR dual-target agonist polypeptides 中山大学 2024-02-02 CN disclosed
WO-2024015717-A2 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS PLIANT THERAPEUTICS, INC. (US) 2024-01-18 WO disclosed
WO-2023211684-A2 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) NOETIX PHARMA LLC (US) 2023-11-02 WO disclosed
US-20230293519-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS PLIANT THERAPEUTICS INC (US) 2023-09-21 US disclosed
EP-2877164-B1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AVALYN PHARMA INC (US) 2023-07-05 EP disclosed
US-20230149375-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. 2023-05-18 US disclosed
US-11559520-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2023-01-24 US disclosed
US-11452718-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2022-09-27 US disclosed
EP-4059499-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF Avalyn Pharma Inc. (US) 2022-09-21 EP disclosed
US-20220218683-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. 2022-07-14 US disclosed
US-11224592-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2022-01-18 US disclosed
US-20210346399-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. (US) 2021-11-11 US disclosed
US-11071741-B2 Aerosol pirfenidone and pyridone analog compound and uses thereof AVALYN PHARMA INC. (US) 2021-07-27 US disclosed
US-20210069165-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. (US) 2021-03-11 US disclosed
US-20200405704-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. (US) 2020-12-31 US disclosed
US-20200306264-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUND AND USES THEREOF AVALYN PHARMA INC. (US) 2020-10-01 US disclosed
US-10610536-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2020-04-07 US disclosed
US-20190054076-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. (US) 2019-02-21 US disclosed
US-20190030012-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. (US) 2019-01-31 US disclosed
US-20180325917-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. (US) 2018-11-15 US disclosed
US-10105356-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2018-10-23 US disclosed
CN-108699037-A NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS 加拉帕戈斯股份有限公司 2018-10-23 CN disclosed
US-10092552-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2018-10-09 US disclosed
US-10028966-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof AVALYN PHARMA INC. (US) 2018-07-24 US disclosed
US-20170275290-A1 PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS INCYTE CORPORATION 2017-09-28 US disclosed
US-9770443-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof GENOA PHARMACEUTICALS, INC. (US) 2017-09-26 US disclosed
US-20170224706-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF GENOA PHARMACEUTICALS, INC. 2017-08-10 US disclosed
EP-3091976-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF Genoa Pharmaceuticals Inc. (US) 2016-11-16 EP disclosed
US-9408836-B2 Pharmaceutical composition containing pirfenidone in sustained-release tablet form Cell Therapy and Technology S.A. DE C.V. (MX) 2016-08-09 US disclosed
US-20150196543-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. 2015-07-16 US disclosed
WO-2015106150-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF GENOA PHARMACEUTICALS INC. (US) 2015-07-16 WO disclosed
EP-2877164-A2 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS Genoa Pharmaceuticals, Inc. (US) 2015-06-03 EP disclosed
US-20140296300-A1 PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION CONTAINING PIRFENIDONE IN SUSTAINED-RELEASE TABLET FORM AND ITS APPLICATION IN THE REGRESSION OF HUMAN CHRONIC RENAL FAILURE, BREAST CAPSULAR CONTRACTURE AND HEPATIC FIBROSIS Cell Therapy and Technology S.A. DE C.V. (MX) 2014-10-02 US disclosed
CN-103735530-A Capsule formulation of pirfenidone and pharmaceutically acceptable excipients INTERMUNE INC 2014-04-23 CN disclosed
WO-2014018668-A2 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF GENOA PHARMACEUTICALS, INC. (US) 2014-01-30 WO disclosed
EP-2670242-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF Genoa Pharmaceuticals, Inc. (US) 2013-12-11 EP disclosed
US-20130310424-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF AVALYN PHARMA INC. 2013-11-21 US disclosed
CN-103393607-A Capsule formulation of pirfenidone and pharmaceutically acceptable excipients INTERMUNE INC 2013-11-20 CN disclosed
WO-2012106382-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF GENOA PHARMACEUTICALS, INC. (US) 2012-08-09 WO disclosed
US-20120192861-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF GENOA PHARMACEUTICALS, INC. (US) 2012-08-02 US disclosed
US-8063055-B2 Substituted pyridone compounds and methods of use AMGEN INC. (US) 2011-11-22 US disclosed
US-20100160312-A1 Substituted Pyridone Compounds and Methods of Use AMGEN INC. (US) 2010-06-24 US disclosed
US-7700607-B2 Substituted pyridone compounds and methods of use AMGEN INC. 2010-04-20 US disclosed
WO-2009149188-A1 COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS INTERMUNE, INC. (US) 2009-12-10 WO disclosed
US-20090286843-A1 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION HOFFMANN-LA ROCHE INC. 2009-11-19 US disclosed
US-20090111982-A1 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION HOFFMANN-LA ROCHE INC. 2009-04-30 US disclosed
US-20090105471-A1 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION HOFFMANN-LA ROCHE INC. 2009-04-23 US disclosed
US-7491794-B2 Macrocyclic compounds as inhibitors of viral replication INTERMUNE, INC. (US) 2009-02-17 US disclosed
US-20080249090-A1 Substituted pyridone compounds and methods of use AMGEN INC. (US) 2008-10-09 US disclosed
EP-1539155-B1 STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION MEPHA AG (CH) 2008-04-02 EP disclosed
US-20070092488-A1 Methods of treating idiopathic pulmonary fibrosis INTERMUNE INC. (US) 2007-04-26 US disclosed
US-20070072181-A1 Combination therapy for treating alphavirus infection and liver fibrosis CORTLAND CAPITAL MARKET SERVICES LLC, AS ADMINISTRATIVE AGENT 2007-03-29 US disclosed
US-20060198823-A1 Compositions and methods for treating viral infections INTERMUNE, INC. 2006-09-07 US disclosed
EP-1261338-B1 COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY CYMAR INC (US) 2006-06-14 EP disclosed
US-20060039931-A1 Stable cream preparations of phenyl-pyridone compounds for topical application MEPHA AG (CH) 2006-02-23 US disclosed
US-20050267018-A1 Macrocyclic compounds as inhibitors of viral replication HOFFMANN-LA ROCHE INC. 2005-12-01 US disclosed
US-6956044-B1 Compositions and methods for treatment of epilepsy INTERMUNE, INC. 2005-10-18 US disclosed
EP-0702551-B1 COMPOSITIONS AND METHODS FOR REPARATION AND PREVENTION OF FIBROTIC LESIONS MARGOLIN SOLOMON B (US) 2002-09-25 EP disclosed
US-5962478-A ADMINISTERING A N-SUBSTITUTED 2(1H)PYRIDONE INTERMUNE, INC. 1999-10-05 US disclosed
US-4052509-A 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE AFFILIATED MEDICAL RESEARCH, INC. (US) 1977-10-04 US disclosed
US-4042699-A 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE AFFILIATED MEDICAL RESEARCH, INC. (US) 1977-08-16 US disclosed
US-3974281-A ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS AFFILIATED MEDICAL RESEARCH, INC. (US) 1976-08-10 US disclosed
US-3974281-A ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS AFFILIATED MEDICAL RESEARCH, INC. (US) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (38 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10105356-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20090111982-A1 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION EIF2AK2, HAVCR2, ZC3HAV1 NOTUM 2635/4885ATM 4224/4885COMT 3198/4885
US-20230149375-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20240299698-A1 PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) CHAT, PNPO, PLPBP NOTUM 2178/4885ATM 293/4885COMT 15/4885
US-20100160312-A1 Substituted Pyridone Compounds and Methods of Use KIT, CMA1, C3AR1 NOTUM 3661/4885ATM 2083/4885COMT 3171/4885
US-10610536-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-11224592-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20230293519-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS ITGB6, ITGA5, ITGAV NOTUM 4179/4885ATM 3420/4885COMT 4803/4885
US-20090286843-A1 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION EIF2AK2, HAVCR2, ZC3HAV1 NOTUM 2635/4885ATM 4224/4885COMT 3198/4885
US-20240122930-A1 INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS ITGB6, ITGA6, ITGAV NOTUM 1834/4885ATM 4226/4885COMT 4604/4885
US-20210069165-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20070092488-A1 Methods of treating idiopathic pulmonary fibrosis IFNG, MMP1, IFNAR1 NOTUM 4102/4885ATM 2914/4885COMT 4709/4885
US-20150196543-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20170275290-A1 PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS MERTK, MAP3K15, MAP3K5 NOTUM 4398/4885ATM 598/4885COMT 2075/4885
US-20060198823-A1 Compositions and methods for treating viral infections IFNAR1, IFNG, TLR3 NOTUM 4268/4885ATM 3974/4885COMT 4118/4885
US-20220218683-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20200405704-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20200306264-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUND AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4418/4885ATM 3168/4885COMT 4769/4885
US-10028966-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20250114376-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-11559520-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20060039931-A1 Stable cream preparations of phenyl-pyridone compounds for topical application PNPO, APOB, PLPBP NOTUM 330/4885ATM 2801/4885COMT 2625/4885
US-20250367178-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20120192861-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20190054076-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-11452718-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20170224706-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20050267018-A1 Macrocyclic compounds as inhibitors of viral replication EIF2AK2, HAVCR2, ZC3HAV1 NOTUM 2635/4885ATM 4224/4885COMT 3198/4885
US-20210346399-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-12023342-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20080249090-A1 Substituted pyridone compounds and methods of use KIT, CMA1, C3AR1 NOTUM 3661/4885ATM 2083/4885COMT 3171/4885
US-20180325917-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20090105471-A1 MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION EIF2AK2, HAVCR2, ZC3HAV1 NOTUM 2635/4885ATM 4224/4885COMT 3198/4885
US-20190030012-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-10092552-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-12226407-B2 Aerosol pirfenidone and pyridone analog compounds and uses thereof PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-20130310424-A1 AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF PLPBP, PIR, PDXK NOTUM 4443/4885ATM 3312/4885COMT 4769/4885
US-11071741-B2 Aerosol pirfenidone and pyridone analog compound and uses thereof PLPBP, PIR, PDXK NOTUM 4418/4885ATM 3168/4885COMT 4769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.