Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142617 | 0.92 | MAPT (0.43) | ATMSHMT2ALDH1A1MAPTKDM4E | |
| SCHEMBL30527364 | 0.84 | BCHE (0.36) | ATMALDH1A1MAPTKDM4EMGLL | |
| SCHEMBL747392 | 0.76 | NOTUM (0.47) | ATMALDH1A1MAPTKDM4EGAA | |
| SCHEMBL11101049 | 0.75 | PSIP1 (0.41) | ATMSHMT2ALDH1A1MAPTKDM4E | |
| SCHEMBL11045550 | 0.75 | ALDH1A1 (0.49) | ATMALDH1A1MAPTKDM4EGAA | |
| SCHEMBL8129211 | 0.74 | KDM4E (0.50) | ATMALDH1A1MAPTKDM4EGAA | |
| SCHEMBL15803829 | 0.72 | SMN1; SMN2 (0.50) | ATMALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL13575331 | 0.72 | ATM (0.47) | ATMALDH1A1MAPTKDM4EGAA | |
| SCHEMBL30228908 | 0.72 | ATM (0.47) | ATMALDH1A1MAPTKDM4EGAA | |
| SCHEMBL10059740 | 0.72 | GAA (0.46) | ATMALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514348-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | Noetix Pharma LLC (US) | 2025-03-05 | — | — | EP | claimed |
| US-20240299698-A1 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | NOETIX PHARMA LLC | 2024-09-12 | — | — | US | claimed |
| WO-2023211684-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | NOETIX PHARMA LLC (US) | 2023-11-02 | — | — | WO | claimed |
| EP-1539155-B1 | STABLE CREAM PREPARATIONS OF PHENYL-PYRIDONE COMPOUNDS FOR TOPICAL APPLICATION | MEPHA AG (CH) | 2008-04-02 | — | — | EP | claimed |
| EP-0866656-B1 | USE OF N-SUBSTITUTED PYRIDONES AS TUMOR NECROSIS FACTOR ALPHA INHIBITORS | MARGOLIN SOLOMON B (US) | 2007-04-25 | — | — | EP | claimed |
| EP-1242084-B1 | TREATMENT OF BREAST CARCINOMAS, ASTROCYTOMAS, MELANOMAS AND RELATED TUMORS | MARGOLIN SOLOMON B (US) | 2006-07-05 | — | — | EP | claimed |
| EP-1261338-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2006-06-14 | — | — | EP | claimed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | claimed |
| EP-1069898-B1 | TOPICAL ANTISEPTIC COMPOSITIONS AND METHODS | MARGOLIN SOLOMON B (US) | 2004-05-12 | — | — | EP | claimed |
| EP-0813409-B1 | TREATMENT OF CYTOKINE GROWTH FACTOR CAUSED DISORDERS | MARGOLIN SOLOMON B (US) | 2004-05-06 | — | — | EP | claimed |
| US-5962478-A | ADMINISTERING A N-SUBSTITUTED 2(1H)PYRIDONE | INTERMUNE, INC. | 1999-10-05 | — | — | US | claimed |
| US-20250367178-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | AVALYN PHARMA INC (US) | 2025-12-04 | — | — | US | disclosed |
| US-20250114376-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | AVALYN PHARMA INC. | 2025-04-10 | — | — | US | disclosed |
| EP-4514348-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | Noetix Pharma LLC (US) | 2025-03-05 | — | — | EP | disclosed |
| US-12226407-B2 | Aerosol pirfenidone and pyridone analog compounds and uses thereof | AVALYN PHARMA INC. (US) | 2025-02-18 | — | — | US | disclosed |
| EP-1261338-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | MEPHA AG (CH) | 2006-02-23 | — | — | US | disclosed |
| US-20050267018-A1 | Macrocyclic compounds as inhibitors of viral replication | HOFFMANN-LA ROCHE INC. | 2005-12-01 | — | — | US | disclosed |
| US-6956044-B1 | Compositions and methods for treatment of epilepsy | INTERMUNE, INC. | 2005-10-18 | — | — | US | disclosed |
| US-5962478-A | ADMINISTERING A N-SUBSTITUTED 2(1H)PYRIDONE | INTERMUNE, INC. | 1999-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299698-A1 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | CHAT, PNPO, PLPBP | ATM 293/4885SHMT2 446/4885ALDH1A1 1343/4885 |
| US-20250114376-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | PLPBP, PIR, PDXK | ATM 3312/4885SHMT2 1677/4885ALDH1A1 167/4885 |
| US-20060039931-A1 | Stable cream preparations of phenyl-pyridone compounds for topical application | PNPO, APOB, PLPBP | ATM 2801/4885SHMT2 1900/4885ALDH1A1 1154/4885 |
| US-20250367178-A1 | AEROSOL PIRFENIDONE AND PYRIDONE ANALOG COMPOUNDS AND USES THEREOF | PLPBP, PIR, PDXK | ATM 3312/4885SHMT2 1677/4885ALDH1A1 167/4885 |
| US-20050267018-A1 | Macrocyclic compounds as inhibitors of viral replication | EIF2AK2, HAVCR2, ZC3HAV1 | ATM 4224/4885SHMT2 3249/4885ALDH1A1 2109/4885 |
| US-12226407-B2 | Aerosol pirfenidone and pyridone analog compounds and uses thereof | PLPBP, PIR, PDXK | ATM 3312/4885SHMT2 1677/4885ALDH1A1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.