Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134476 | 0.81 | PIM1 (0.43) | CDC7HPGDKDM4EALDH1A1PARP1 | |
| SCHEMBL12092839 | 0.80 | CDC7 (0.52) | CDC7ALDH1A1PARP1PIM1SMN1; SMN2 | |
| SCHEMBL15009288 | 0.79 | CDC7 (0.54) | CDC7KDM4EALDH1A1PIM1SMN1; SMN2 | |
| SCHEMBL4192947 | 0.77 | CDC7 (0.52) | CDC7ALDH1A1PIM1 | |
| SCHEMBL22716058 | 0.77 | CDC7 (0.49) | CDC7HPGDKDM4EALDH1A1PARP1 | |
| SCHEMBL2572340 | 0.75 | CDC7 (0.50) | CDC7ALDH1A1PIM1 | |
| SCHEMBL2520510 | 0.74 | CDC7 (0.46) | CDC7ALDH1A1PIM1SMN1; SMN2LMNA | |
| SCHEMBL30229287 | 0.72 | CDC7 (0.47) | CDC7KDM4EALDH1A1PARP1PIM1 | |
| SCHEMBL19902330 | 0.72 | CDC7 (0.44) | CDC7ALDH1A1MGLLPIM1SMN1; SMN2 | |
| SCHEMBL14864849 | 0.70 | CDC7 (0.58) | CDC7ALDH1A1PARP1PIM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | claimed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | claimed |