Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15009288 | 0.86 | CDC7 (0.54) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL12092839 | 0.84 | CDC7 (0.52) | CDC7RPS6KA3ALDH1A1GAAPIM1 | |
| SCHEMBL2572340 | 0.82 | CDC7 (0.50) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL22716058 | 0.81 | CDC7 (0.49) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL30229243 | 0.77 | CDC7 (0.46) | CDC7ALDH1A1PIM1 | |
| SCHEMBL2520510 | 0.77 | CDC7 (0.46) | CDC7RPS6KA3ALDH1A1PIM1PIM2 | |
| SCHEMBL20399819 | 0.77 | CDC7 (0.58) | CDC7RPS6KA3ALDH1A1GAAPIM1 | |
| SCHEMBL19902330 | 0.76 | CDC7 (0.44) | CDC7RPS6KA3ALDH1A1PIM1PIM2 | |
| SCHEMBL24276957 | 0.73 | CDC7 (0.58) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL14864849 | 0.73 | CDC7 (0.58) | CDC7RPS6KA3ALDH1A1GAAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | claimed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | claimed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-7476666-B2 | HIV integrase inhibitors | MERCK & CO., INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080015187-A1 | Hiv Integrase Inhibitors | MERCK SHARP & DOHME CORP. | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015187-A1 | Hiv Integrase Inhibitors | REV1, ZC3HAV1, PNP | CDC7 435/4885RPS6KA3 598/4885GSK3B 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.