Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19902330 | 0.90 | CDC7 (0.44) | CDC7RPS6KA3ALDH1A1KMT2AJMJD6 | |
| SCHEMBL22716058 | 0.85 | CDC7 (0.49) | CDC7ADORA3ALDH1A1KMT2AJMJD6 | |
| SCHEMBL19902329 | 0.84 | CDC7 (0.41) | CDC7RPS6KA3ALDH1A1KMT2APIM1 | |
| SCHEMBL29256111 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KMT2ALMNACYP1A2CYP2C19 | |
| SCHEMBL12092839 | 0.80 | CDC7 (0.52) | CDC7RPS6KA3ALDH1A1KMT2APIM1 | |
| SCHEMBL15009288 | 0.79 | CDC7 (0.54) | CDC7ALDH1A1PIM1PIM2SMN1; SMN2 | |
| SCHEMBL4192947 | 0.77 | CDC7 (0.52) | CDC7RPS6KA3ALDH1A1PIM1PIM2 | |
| SCHEMBL23980134 | 0.77 | CYP1A2 (0.46) | ADORA3ALDH1A1L3MBTL1KMT2ACYP1A2 | |
| SCHEMBL3127245 | 0.77 | ALDH1A1 (0.46) | CDC7ADORA3RPS6KA3ALDH1A1KMT2A | |
| SCHEMBL6385372 | 0.77 | CYP1A2 (0.44) | ADORA3ALDH1A1L3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479831-B2 | Substituted N(-methyl-D3)pyridazine-3-carboxamide or M-(methyl-D3)-nicotinamide compounds as IL-12, IL-23 and/or IFNα modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-11-25 | — | — | US | disclosed |
| US-20250270223-A1 | CRYSTAL OF SUBSTITUTED PIPERAZINE DERIVATIVE AND PREPARATION METHOD THEREFOR | Kangbaida (Sichuan) Biotechnology Co., Ltd (CN) | 2025-08-28 | — | — | US | disclosed |
| EP-4504728-A1 | PYRAZOLOPYRAZINONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-02-12 | — | — | EP | disclosed |
| US-20240383868-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-11-21 | — | — | US | disclosed |
| CN-118946563-A | Pyrazolopyrazinone compounds, process for their preparation and their therapeutic use | 赛诺菲 | 2024-11-12 | — | — | CN | disclosed |
| CN-118434744-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-08-02 | — | — | CN | disclosed |
| US-20240158406-A1 | PIPERAZINE DERIVATIVE AND USE THEREOF IN MEDICINE | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2024-05-16 | — | — | US | disclosed |
| EP-4342896-A1 | PIPERAZINE DERIVATIVE AND USE THEREOF IN MEDICINE | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2024-03-27 | — | — | EP | disclosed |
| CN-117586263-A | Piperazine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20240034723-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-02-01 | — | — | US | disclosed |
| US-20120295913-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY | 2012-11-22 | — | — | US | disclosed |
| US-20120295913-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY | 2012-11-22 | — | — | US | disclosed |
| US-20120225844-A1 | BICYCLIC TRIAZOLE AND PYRAZOLE LACTAMS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | JANSSEN-CILAG S.A. (ES) | 2012-09-06 | — | — | US | disclosed |
| US-20120225844-A1 | BICYCLIC TRIAZOLE AND PYRAZOLE LACTAMS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | JANSSEN-CILAG S.A. (ES) | 2012-09-06 | — | — | US | disclosed |
| WO-2012083224-A1 | BICYCLIC TRIAZOLE AND PYRAZOLE LACTAMS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012078817-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2011130163-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011130163-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |
| US-20110251184-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251184-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270223-A1 | CRYSTAL OF SUBSTITUTED PIPERAZINE DERIVATIVE AND PREPARATION METHOD THEREFOR | WEE1, WEE2, WASF2 | CDC7 3034/4885ADORA3 4352/4885RPS6KA3 3714/4885 |
| US-20110251184-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | HDAC6, HDAC1, H1-3 | CDC7 3550/4885ADORA3 1818/4885RPS6KA3 1071/4885 |
| US-12479831-B2 | Substituted N(-methyl-D3)pyridazine-3-carboxamide or M-(methyl-D3)-nicotinamide compounds as IL-12, IL-23 and/or IFNα modulators | TYK2, IRAK3, JAK3 | CDC7 3419/4885ADORA3 324/4885RPS6KA3 246/4885 |
| US-20240383868-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | CDC7 1189/4885ADORA3 3738/4885RPS6KA3 2572/4885 |
| US-20240034723-A1 | PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | IKZF2, IKZF1, NUTF2 | CDC7 3875/4885ADORA3 4616/4885RPS6KA3 4056/4885 |
| US-20120225844-A1 | BICYCLIC TRIAZOLE AND PYRAZOLE LACTAMS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | GRM5, GRIK5, GRIN3A | CDC7 3768/4885ADORA3 139/4885RPS6KA3 908/4885 |
| US-20240158406-A1 | PIPERAZINE DERIVATIVE AND USE THEREOF IN MEDICINE | VHL, GLS2, GOT2 | CDC7 4657/4885ADORA3 2786/4885RPS6KA3 1435/4885 |
| US-20120295913-A1 | BICYCLIC PYRAZOLE COMPOUNDS AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | GRM5, GRIK5, GRM3 | CDC7 4213/4885ADORA3 120/4885RPS6KA3 1630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.