Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25185951 | 0.90 | DPP4 (0.38) | MEN1KMT2A | |
| SCHEMBL30510237 | 0.90 | DPP4 (0.38) | MEN1KMT2A | |
| SCHEMBL27078253 | 0.88 | ALDH1A1 (0.35) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL25182298 | 0.88 | PPIA (0.33) | TSHR | |
| SCHEMBL30510307 | 0.88 | ALDH1A1 (0.35) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27215385 | 0.87 | PPIA (0.41) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL25186515 | 0.87 | PPIA (0.41) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4600010 | 0.83 | LDHA (0.47) | GAAKMT2A | |
| SCHEMBL30510242 | 0.83 | LDHA (0.47) | GAAKMT2A | |
| SCHEMBL30510418 | 0.82 | PPIA (0.37) | KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373835-A1 | MACROCYLIC IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |