Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885665 | 0.82 | ADRB2 (0.50) | ADRB2HTR2AACACBPDE2AFFAR1 | |
| SCHEMBL27207787 | 0.82 | ADRB2 (0.50) | ADRB2HTR2AACACBPDE2AFFAR1 | |
| SCHEMBL27207789 | 0.74 | ADRB2 (0.54) | ADRB2HTR2AACACBPDE2AFFAR1 | |
| SCHEMBL30885664 | 0.74 | ADRB2 (0.54) | ADRB2HTR2AACACBPDE2AFFAR1 | |
| SCHEMBL19036905 | 0.74 | GRM5 (0.43) | HTR2AACACBHPGDCYP3A4CYP2C9 | |
| SCHEMBL19629002 | 0.71 | CYP3A4 (0.38) | HTR2AACACBCYP3A4CYP2C9FFAR1 | |
| SCHEMBL23511786 | 0.70 | ALDH1A1 (0.41) | ACACBALDH1A1GAAHPGDALOX15 | |
| SCHEMBL25053676 | 0.70 | ACACB (0.36) | ACACB | |
| SCHEMBL26748745 | 0.69 | ACACB (0.39) | ACACB | |
| SCHEMBL162942 | 0.68 | ACACB (0.60) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395549-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | Oerth Bio LLC (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | OERTH BIO LLC (US) | 2023-03-09 | — | — | WO | disclosed |