SCHEMBL30230010

SCHEMBL30230010

CN(C(=O)c1ccc2c(c1)OC(F)(F)O2)c1cccc(C(=O)O)c1F

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 3/20 0.45
WNT3A P56704 3/20 0.45
MRGPRX4 Q96LA9 1/20 0.39
KIT P10721 1/20 0.36
BRAF P15056 1/20 0.36
SMYD3 Q9H7B4 3/20 0.36
ACLY P53396 1/20 0.34
CFTR P13569 3/20 0.34
AURKA O14965 1/20 0.34
AURKB Q96GD4 1/20 0.34
HDAC4 P56524 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21899377 1.00 CTNNB1 (0.45) CTNNB1WNT3AMRGPRX4KITBRAF
SCHEMBL21965336 0.90 CTNNB1 (0.42) CTNNB1WNT3AMRGPRX4KITBRAF
SCHEMBL30776135 0.90 CTNNB1 (0.42) CTNNB1WNT3AMRGPRX4KITBRAF
SCHEMBL21965723 0.90 CTNNB1 (0.42) CTNNB1WNT3AMRGPRX4KITBRAF
SCHEMBL21899368 0.88 CTNNB1 (0.40) CTNNB1WNT3AMRGPRX4KITBRAF
SCHEMBL21965340 0.79 HTT (0.42) CTNNB1WNT3AKITBRAFSMYD3
SCHEMBL1805191 0.78 OPRM1 (0.48) ACLYKDM4E
SCHEMBL1804980 0.78 KDM4E (0.45) ACLYKDM4EALDH1A1
SCHEMBL1802624 0.77 ACLY (0.43) ACLYKDM4EALDH1A1
SCHEMBL21965335 0.77 HTT (0.36) CTNNB1WNT3AKITBRAFSMYD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872901-B Imine compound and application thereof 沈阳中化农药化工研发有限公司 2024-11-12 CN disclosed
CN-115872901-A Imine compound and application thereof 沈阳中化农药化工研发有限公司 2023-03-31 CN disclosed