Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19526669 | 0.80 | PTGER4 (0.52) | PTGER4ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL23286926 | 0.80 | PTGER4 (0.56) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL20266373 | 0.80 | PTGER4 (0.64) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL25933702 | 0.78 | PTGER4 (0.61) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL2770793 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ERN1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL20594457 | 0.77 | KDM4E (0.67) | ALDH1A1MAPTERN1KDM4EHSD17B10 | |
| SCHEMBL29825520 | 0.77 | PTGER4 (0.80) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL2249029 | 0.77 | PTGER4 (0.80) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL25314456 | 0.77 | PTGER4 (0.56) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23577769 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTRAB9AERN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395549-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | Oerth Bio LLC (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | OERTH BIO LLC (US) | 2023-03-09 | — | — | WO | disclosed |