Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23287173 | 0.88 | PTGER4 (0.70) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23490760 | 0.88 | PTGER4 (0.51) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL25933702 | 0.84 | PTGER4 (0.61) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL2249029 | 0.82 | PTGER4 (0.80) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL20266373 | 0.82 | PTGER4 (0.64) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL29825520 | 0.82 | PTGER4 (0.80) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL25314456 | 0.82 | PTGER4 (0.56) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL30230127 | 0.80 | PTGER4 (0.51) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL24214196 | 0.79 | PTGER4 (0.53) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL26987784 | 0.79 | PTGER4 (0.53) | PTGER4ALDH1A1MAPTRAB9AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702404-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210171499-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2021-06-10 | — | — | US | disclosed |
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702404-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | PTGER4 996/4885ALDH1A1 3556/4885MAPT 3314/4885 |
| US-20210171499-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | PTGER4 996/4885ALDH1A1 3556/4885MAPT 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.