SCHEMBL302307

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL302308	1.00	MAPT (0.50)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303824	0.89	GAA (0.43)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303823	0.89	GAA (0.43)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL302589	0.89	FES (0.49)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303500	0.89	TYK2 (0.42)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303499	0.89	TYK2 (0.42)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL302588	0.89	FES (0.49)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303778	0.86	MAPT (0.57)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303765	0.86	MAPT (0.52)	MAPTKDM4EGAAALDH1A1HPGD
	SCHEMBL303779	0.86	MAPT (0.57)	MAPTKDM4EGAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.