Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.58 |
| ▸ | RAMP1 | O60894 | 11/20 | 0.58 |
| ▸ | CALCA | P06881 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13081133 | 0.80 | CALCA (0.54) | CALCRLRAMP1CALCACYP3A4 | |
| SCHEMBL3282021 | 0.80 | CALCA (0.60) | CALCRLCALCACYP3A4 | |
| SCHEMBL3595749 | 0.80 | CALCA (0.58) | CALCRLCALCACYP3A4 | |
| SCHEMBL3607821 | 0.79 | CALCRL (0.76) | CALCRLCALCACYP3A4 | |
| SCHEMBL3607815 | 0.79 | CALCRL (0.76) | CALCRLCALCACYP3A4 | |
| SCHEMBL3237433 | 0.79 | CHRM4 (0.57) | CALCRLRAMP1CALCACHRM4 | |
| SCHEMBL29872644 | 0.79 | CALCRL (0.54) | CALCRLRAMP1CALCACHRM4 | |
| SCHEMBL13762761 | 0.79 | CALCRL (0.54) | CALCRLRAMP1CALCACHRM4 | |
| SCHEMBL13080979 | 0.79 | CALCRL (0.54) | CALCRLCALCACYP3A4 | |
| SCHEMBL3591393 | 0.79 | CALCA (0.57) | CALCRLCALCACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034466-A1 | CGRP ANTAGONISTS FOR TREATING PSORIASIS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2023-03-09 | — | — | WO | claimed |
| WO-2023034466-A1 | CGRP ANTAGONISTS FOR TREATING PSORIASIS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2023-03-09 | — | — | WO | disclosed |