SCHEMBL30231309

SCHEMBL30231309

CSCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCSC)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.62
▸ CALCR P30988 4/20 0.59
▸ MAPK8 P45983 1/20 0.57
▸ MAPK9 P45984 1/20 0.57
▸ MAPK10 P53779 1/20 0.57
▸ CTSL P07711 3/20 0.57
▸ CTSS P25774 3/20 0.57
▸ CTSK P43235 3/20 0.57
▸ CTSH P09668 1/20 0.57
▸ GLP1R P43220 7/20 0.54
▸ GCGR P47871 7/20 0.54
▸ KEAP1 Q14145 1/20 0.54
▸ GIPR P48546 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934240 0.97 APLNR (0.61) APLNRCALCRMAPK8MAPK9MAPK10
SCHEMBL30567779 0.92 CALCR (0.64) APLNRCALCRMAPK8MAPK9MAPK10
SCHEMBL30231481 0.90 CALCR (0.71) APLNRCALCRGLP1RGCGRGIPR
SCHEMBL30219087 0.90 CALCR (0.71) APLNRCALCRGLP1RGCGRGIPR
Acetic Acid SCHEMBL30219069 0.89 CALCR (0.70) APLNRCALCRGLP1RGCGRGIPR
Acetic Acid SCHEMBL30219088 0.89 CALCR (0.70) APLNRCALCRGLP1RGCGRGIPR
SCHEMBL30219064 0.89 CALCR (0.71) APLNRCALCRGLP1RGCGRGIPR
SCHEMBL30231506 0.89 CALCR (0.71) APLNRCALCRGLP1RGCGRGIPR
SCHEMBL29934195 0.89 GLP1R (0.51) APLNRCALCRGLP1RGCGRKEAP1
SCHEMBL31255142 0.88 CALCR (0.66) APLNRCALCRMAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102332-A1 NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF Blaze Bioscience, Inc. (US) 2026-05-15 — — WO disclosed
US-12048732-B2 Methods of treating breast cancer Blaze Bioscience, Inc. (US) 2024-07-30 — — US disclosed
US-20230257428-A1 METHODS OF TREATMENT USING CHLOROTOXIN CONJUGATES Blaze Bioscience, Inc. 2023-08-17 — — US disclosed
US-20230037660-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS Blaze Bioscience, Inc. 2023-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257428-A1 METHODS OF TREATMENT USING CHLOROTOXIN CONJUGATES CHLSN, SLC47A1, CLSPN APLNR 630/4885CALCR 1387/4885MAPK8 4785/4885
US-20230037660-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS FLT4, FLT1, KDR APLNR 222/4885CALCR 452/4885MAPK8 3773/4885
US-12048732-B2 Methods of treating breast cancer BRCA1, HUNK, MLEC APLNR 373/4885CALCR 1367/4885MAPK8 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback