Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | TYK2 | P29597 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24003821 | 1.00 | ACVRL1 (0.62) | ACVRL1MAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL24004060 | 0.91 | POLB (0.72) | ACVRL1MAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL25822055 | 0.87 | MAPT (0.74) | ACVRL1MAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL30828582 | 0.83 | KDM4E (0.85) | MAPTPOLBKDM4EL3MBTL1MAPK1 | |
| SCHEMBL30828552 | 0.83 | KDM4E (0.85) | MAPTPOLBKDM4EL3MBTL1MAPK1 | |
| SCHEMBL23999623 | 0.83 | KDM4E (0.85) | MAPTPOLBKDM4EL3MBTL1MAPK1 | |
| SCHEMBL23999629 | 0.82 | MAPT (0.63) | MAPTPOLBKDM4EL3MBTL1MAPK1 | |
| SCHEMBL23999624 | 0.82 | MAPT (0.63) | MAPTPOLBKDM4EL3MBTL1MAPK1 | |
| SCHEMBL24006426 | 0.82 | ACVRL1 (0.53) | ACVRL1MAPTPOLBNT5EJAK2 | |
| SCHEMBL24003854 | 0.81 | KCNK3 (0.69) | MAPTPOLBKDM4EL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996939-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-4146666-A1 | AKT3 MODULATORS | Georgiamune LLC (US) | 2023-03-15 | — | — | EP | disclosed |