Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818540 | 0.81 | PARP1 (0.62) | MEN1KMT2AGAACNR2PARP1 | |
| SCHEMBL14958590 | 0.73 | MGAM (0.50) | GAA | |
| SCHEMBL17840165 | 0.72 | RORC (0.57) | MAPTL3MBTL1CNR2KDM4EHPGD | |
| SCHEMBL1894334 | 0.70 | PARP1 (0.67) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL8818566 | 0.70 | PARP1 (0.60) | GAACNR2PARP1SCN2AMAPK13 | |
| SCHEMBL1663645 | 0.70 | MEN1 (0.97) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL9504942 | 0.70 | MEN1 (0.63) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL21894108 | 0.70 | MEN1 (0.63) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL30989189 | 0.70 | MEN1 (0.63) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL3968268 | 0.70 | MEN1 (0.63) | MEN1KMT2APOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055124-A1 | BICYCLIC FUSED RING DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사유한양행 | 2023-04-06 | — | — | WO | disclosed |