Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314619 | 1.00 | CHEK1 (0.47) | CHEK1PIM1CFTRMAPK8JAK2 | |
| SCHEMBL28032605 | 0.87 | CHEK1 (0.52) | CHEK1CFTRMAPK8EPHX2SCN9A | |
| SCHEMBL4091950 | 0.86 | CHEK1 (0.47) | CHEK1PIM1MAPK8JAK2EPHX2 | |
| SCHEMBL22497443 | 0.86 | ALDH1A1 (0.57) | PIM1CFTREPHX2KDM4EHSD17B10 | |
| SCHEMBL6518415 | 0.86 | CHEK1 (0.49) | CHEK1PIM1MAPK8JAK2EPHX2 | |
| SCHEMBL28128209 | 0.84 | MAPK8 (0.48) | CHEK1MAPK8EPHX2KDM4EHSD17B10 | |
| SCHEMBL7685381 | 0.83 | CFTR (0.65) | PIM1CFTREPHX2KDM4EHSD17B10 | |
| SCHEMBL22092981 | 0.83 | DGAT1 (0.51) | CHEK1PIM1MAPK8JAK2EPHX2 | |
| SCHEMBL965069 | 0.81 | CHEK1 (0.46) | CHEK1PIM1MAPK8JAK2EPHX2 | |
| SCHEMBL9901975 | 0.81 | AKR1C2 (0.47) | CHEK1PIM1MAPK8JAK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4120837-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 2-(3-PHENYLUREIDO)BENZAMIDE, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |