Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574905 | 1.00 | GPR119 (0.53) | GPR119PDE10AALOX5APFEN1 | |
| SCHEMBL23928943 | 0.87 | FNTA (0.48) | GPR119PDE10AALOX5APFEN1 | |
| SCHEMBL25971057 | 0.87 | GPR119 (0.53) | GPR119 | |
| SCHEMBL24455270 | 0.84 | GPR119 (0.57) | GPR119 | |
| SCHEMBL29573807 | 0.83 | GPR119 (0.49) | GPR119 | |
| SCHEMBL26484114 | 0.83 | GPR119 (0.49) | GPR119 | |
| SCHEMBL24498579 | 0.82 | GPR119 (0.56) | GPR119 | |
| SCHEMBL22932970 | 0.82 | GPR119 (0.54) | GPR119PDE10A | |
| SCHEMBL20266521 | 0.82 | GPR119 (0.56) | GPR119PDE10A | |
| SCHEMBL29556921 | 0.82 | GPR119 (0.56) | GPR119PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667238-B | Five-membered ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-115667238-A | Five-membered ring derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-01-31 | — | — | CN | disclosed |