SCHEMBL23928943

SCHEMBL23928943

CC(C)(C)OC(=O)N1CCC(c2cccnc2OCc2ccc(Cl)cc2F)CC1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.48
FNTB P49356 2/20 0.48
PDE10A Q9Y233 1/20 0.48
CYP3A4 P08684 1/20 0.46
CYP3A5 P20815 1/20 0.46
GPR119 Q8TDV5 4/20 0.45
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
USP30 Q70CQ3 1/20 0.43
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
TP53 P04637 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
DPP4 P27487 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23928974 0.88 FNTA (0.46) FNTAFNTBCYP3A4CYP3A5GPR119
SCHEMBL30237690 0.87 GPR119 (0.53) PDE10AGPR119ALOX5APFEN1
SCHEMBL24574905 0.87 GPR119 (0.53) PDE10AGPR119ALOX5APFEN1
SCHEMBL23235671 0.87 P2RX7 (0.45)
SCHEMBL23929009 0.85 GPR119 (0.51) FNTAFNTBCYP3A4CYP3A5GPR119
SCHEMBL24320996 0.84 GLP1R (0.53) CYP3A4CYP3A5GPR119USP30MAPT
SCHEMBL30583912 0.83 DPP4 (0.45) FNTAFNTBCYP3A4CYP3A5GPR119
SCHEMBL28786494 0.83 DPP4 (0.46) FNTAFNTBCYP3A4CYP3A5GPR119
SCHEMBL28543738 0.83 P2RX7 (0.43)
SCHEMBL24321002 0.82 GPR119 (0.46) CYP3A4CYP3A5GPR119POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270196-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2025-08-28 US disclosed
US-12331041-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2025-06-17 US disclosed
US-20240132483-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2024-04-25 US disclosed
US-11858916-B2 GLP-1 receptor agonists and uses thereof PFIZER INC. (US) 2024-01-02 US disclosed
EP-3806855-B1 GLP-1 RECEPTOR AGONISTS AND USES THEREOF PFIZER (US) 2023-03-01 EP disclosed
US-20210332034-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331041-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885PDE10A 284/4885
US-11858916-B2 GLP-1 receptor agonists and uses thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885PDE10A 284/4885
US-20240132483-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885PDE10A 284/4885
US-20210332034-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885PDE10A 284/4885
US-20250270196-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR FNTA 3648/4885FNTB 3558/4885PDE10A 284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.