Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966553 | 0.92 | CTSV (0.55) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL27216346 | 0.91 | CTSV (0.44) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL27216351 | 0.91 | CTSV (0.44) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL27216337 | 0.91 | CTSV (0.55) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL30935101 | 0.91 | CTSV (0.55) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL27216376 | 0.91 | CTSV (0.57) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL30966533 | 0.91 | CTSV (0.55) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL30236943 | 0.91 | CTSV (0.57) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL27216342 | 0.91 | CTSV (0.55) | CTSVCYP3A4CTSSCTSK | |
| SCHEMBL27216377 | 0.91 | CTSV (0.57) | CTSVCYP3A4CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336610-A1 | 3CL PROTEASE SMALL-MOLECULE INHIBITOR FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | THE GLOBAL HEALTH DRUG DISCOVERY INSTITUTE (CN) | 2024-10-10 | — | — | US | disclosed |
| EP-4368610-A1 | 3CL PROTEASE SMALL-MOLECULE INHIBITOR FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | The Global Health Drug Discovery Institute (CN) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023011443-A1 | 3CL PROTEASE SMALL-MOLECULE INHIBITOR FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | 北京华益健康药物研究中心 | 2023-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336610-A1 | 3CL PROTEASE SMALL-MOLECULE INHIBITOR FOR TREATING OR PREVENTING CORONAVIRUS INFECTION, AND USE THEREOF | ACE, ACE2, SPINT2 | CTSV 67/4885CYP3A4 90/4885CTSS 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.