Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A2 | O43868 | 4/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30237821 | 0.92 | HSPA8 (0.52) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30237383 | 0.92 | SLC28A2 (0.56) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13834974 | 0.92 | SLC28A2 (0.68) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13834979 | 0.92 | SLC28A2 (0.68) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30237368 | 0.91 | RAPGEF3 (0.61) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5328067 | 0.91 | RAPGEF3 (0.61) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30237176 | 0.91 | HSPA8 (0.56) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5328057 | 0.91 | RAPGEF3 (0.61) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30237448 | 0.91 | HSD17B10 (0.56) | SLC28A2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30237424 | 0.90 | SLC28A2 (0.58) | SLC28A2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION | 2023-09-14 | — | — | US | disclosed |
| US-11680264-B2 | Methods of modulating melanosome pH and melanin level in cells | CORNELL UNIVERSITY (US) | 2023-06-20 | — | — | US | disclosed |
| WO-2023039578-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | OMEROS CORPORATION (US) | 2023-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285556-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | TP53, CD4, MCL1 | SLC28A2 3624/4885PDE4A 2291/4885PDE4B 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.