SCHEMBL30239598

SCHEMBL30239598

COc1ccccc1[C@H](C)N[S@+]([O-])C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
ACHE P22303 2/20 0.46
HTR2A P28223 4/20 0.39
SLC6A4 P31645 3/20 0.39
CYP2D6 P10635 2/20 0.38
CA12 O43570 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KCNH2 Q12809 1/20 0.35
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
LPAR1 Q92633 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28578527 0.85 KCNK3 (0.39) CA1CA2ACHEHTR2ASLC6A4
SCHEMBL28576077 0.85 KCNK3 (0.39) CA1CA2ACHEHTR2ASLC6A4
SCHEMBL28576079 0.85 KCNK3 (0.39) CA1CA2ACHEHTR2ASLC6A4
SCHEMBL28578530 0.85 KCNK3 (0.39) CA1CA2ACHEHTR2ASLC6A4
SCHEMBL21459049 0.81 LMNA (0.36) HTR2ASLC6A4CYP2D6HPGDSMN1; SMN2
SCHEMBL21405086 0.81 LMNA (0.36) HTR2ASLC6A4CYP2D6HPGDSMN1; SMN2
SCHEMBL21405088 0.81 LMNA (0.36) HTR2ASLC6A4CYP2D6HPGDSMN1; SMN2
SCHEMBL21459051 0.81 LMNA (0.36) HTR2ASLC6A4CYP2D6HPGDSMN1; SMN2
SCHEMBL2004178 0.81 LMNA (0.36) HTR2ASLC6A4CYP2D6HPGDSMN1; SMN2
SCHEMBL29138194 0.81 CYP2D6 (0.43) CA1CA2ACHECYP2D6HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518166-B Peptidomimetics compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof 中国药科大学 2023-01-31 CN disclosed