Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329204 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3711581 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL29924638 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL20783923 | 0.80 | KMT2A (0.41) | ALDH1A1TP53SMN1; SMN2RAB9AMAPT | |
| SCHEMBL25604729 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1TP53SMN1; SMN2RAB9AMAPT | |
| SCHEMBL20101093 | 0.77 | IDO1 (0.58) | ALDH1A1SMN1; SMN2RAB9AMAPTGFER | |
| SCHEMBL9885168 | 0.74 | SMN1; SMN2 (0.71) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL2899732 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL29462442 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TP53CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL20101052 | 0.73 | SMN1; SMN2 (0.58) | ALDH1A1CYP3A4SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2025011617-A1 | FUSED HETEROAROMATIC RING COMPOUND, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州圣域生物医药科技有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-109071528-B | Bicyclic compounds for diagnosis and therapy | AC免疫有限公司 | 2023-02-17 | — | — | CN | disclosed |