Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144076 | 1.00 | SIRT6 (0.46) | SIRT6KMT2ANNMTAPPPDE4A | |
| SCHEMBL31108226 | 0.84 | KDM4E (0.53) | KMT2AMAPK1KDM4EL3MBTL1TSHR | |
| SCHEMBL27080246 | 0.84 | KDM4E (0.53) | KMT2AMAPK1KDM4EL3MBTL1TSHR | |
| SCHEMBL9377198 | 0.83 | MAPK1 (0.59) | KMT2AMAPK1KDM4EL3MBTL1HRH3 | |
| SCHEMBL8953636 | 0.80 | KMT2A (0.49) | SIRT6KMT2ANNMTAPPPDE4A | |
| SCHEMBL16465368 | 0.80 | KMT2A (0.53) | SIRT6KMT2ANNMTAPPPDE4A | |
| SCHEMBL19304062 | 0.80 | MAPK1 (0.37) | SIRT6PDE4AMAPK1KDM4EL3MBTL1 | |
| SCHEMBL6469006 | 0.79 | KMT2A (0.47) | SIRT6KMT2ANNMTAPPPDE4A | |
| SCHEMBL3923712 | 0.79 | PDE4A (0.43) | SIRT6KMT2ANNMTAPPPDE4A | |
| SCHEMBL2655434 | 0.76 | FFAR1 (0.35) | SIRT6NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |
| US-11566026-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566026-B2 | Heterocyclic compounds as immunomodulators | CD74, IL2, ICOS | SIRT6 1563/4885KMT2A 4066/4885NNMT 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.