Tenamfetamine

Tenamfetamine

SCHEMBL30242515

C[C@H](N)Cc1ccc2c(c1)OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 1.00
SLC6A4 P31645 3/20 1.00
SLC6A2 P23975 2/20 1.00
SLC6A3 Q01959 2/20 1.00
CYP2D6 P10635 2/20 0.66
CYP3A4 P08684 2/20 0.60
NPSR1 Q6W5P4 1/20 0.59
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tenamfetamine SCHEMBL9361151 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL29392330 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30242630 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30904507 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL15162053 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL393456 1.00 TAAR1 (1.00) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30203543 0.98 TAAR1 (0.97) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL30401290 0.98 TAAR1 (0.97) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
Tenamfetamine SCHEMBL5305879 0.98 TAAR1 (0.97) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL22885190 0.89 TAAR1 (0.81) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998433-A Method for producing R-MDMA 思维医学股份有限公司 2025-05-13 CN claimed
EP-4615828-A2 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EmpathBio, Inc. (US) 2025-09-17 EP disclosed
EP-4615828-A2 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EmpathBio, Inc. (US) 2025-09-17 EP disclosed
EP-4551680-A2 METHODS OF MANUFACTURE OF R-MDMA Mind Medicine, Inc. (US) 2025-05-14 EP disclosed
CN-119998433-A Method for producing R-MDMA 思维医学股份有限公司 2025-05-13 CN disclosed
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
JP-2025502054-A ユニヴェルシテートスピタル バーゼル 2025-01-24 JP disclosed
CN-119013009-A R-MDMA and S-MDMA for use in adjuvant psychological therapy 巴塞尔大学医院 2024-11-22 CN disclosed
EP-4408407-A1 ENANTIOMERIC RATIOS OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE AND RELATED METABOLITES AND USES THEREOF atai Life Sciences AG (DE) 2024-08-07 EP disclosed
US-20240208920-A1 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EMPATHBIO, INC. 2024-06-27 US disclosed
US-20240208920-A1 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EMPATHBIO, INC. 2024-06-27 US disclosed
WO-2024102845-A3 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EMPATHBIO, INC. (US) 2024-06-20 WO disclosed
WO-2024102845-A2 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EMPATHBIO, INC. (US) 2024-05-16 WO disclosed
WO-2024102845-A2 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS EMPATHBIO, INC. (US) 2024-05-16 WO disclosed
WO-2024011067-A2 METHODS OF MANUFACTURE OF R-MDMA Mind Medicine, Inc. (US) 2024-01-11 WO disclosed
US-20230129723-A1 ENANTIOMERIC RATIOS OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE AND RELATED METABOLITES AND USES THEREOF EMPATHBIO, INC. 2023-04-27 US disclosed
WO-2023056472-A1 ENANTIOMERIC RATIOS OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE AND RELATED METABOLITES AND USES THEREOF ATAI Life Sciences AG (DE) 2023-04-06 WO disclosed
US-20230097530-A1 ENANTIOMERIC RATIOS OF 3,4-METHYLENEDIOXYMETHAMPHETAMINE AND RELATED METABOLITES AND USES THEREOF EMPATHBIO, INC. 2023-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208920-A1 SYNTHESIS OF MDA OR ITS OPTICALLY ACTIVE (R)- OR (S)-MDA ISOMERS COMT, PNMT, DDT TAAR1 149/4885SLC6A4 109/4885SLC6A2 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.