Acetyltributyl Citrate

Acetyltributyl Citrate

SCHEMBL3024447

CCCCOC(=O)CC(CC(=O)OCCCC)(OC(C)=O)C(=O)OCCCC.N#N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
NAAA Q02083 1/20 0.40
ATM Q13315 1/20 0.37
DGKA P23743 1/20 0.36
TSHR P16473 4/20 0.35
HPGD P15428 1/20 0.35
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
FAAH O00519 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HCAR2 Q8TDS4 1/20 0.33
HTR2C P28335 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyltributyl Citrate SCHEMBL23183 0.97 ALDH1A1 (0.50) ALDH1A1NAAAATMDGKATSHR
SCHEMBL15695761 0.92 ALDH1A1 (0.46) ALDH1A1NAAAATMDGKATSHR
SCHEMBL966165 0.92 NAAA (0.49) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL2986769 0.91 ALDH1A1 (0.44) ALDH1A1NAAAATMDGKATSHR
Acetyltributyl Citrate SCHEMBL28859309 0.91 ALDH1A1 (0.44) ALDH1A1NAAAATMDGKATSHR
SCHEMBL1957839 0.91 NAAA (0.51) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL17812757 0.91 NAAA (0.51) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL17812732 0.91 NAAA (0.51) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL17812645 0.91 NAAA (0.51) ALDH1A1NAAADGKATSHRRAD52
SCHEMBL17812705 0.91 NAAA (0.51) ALDH1A1NAAADGKATSHRRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041230-B2 A PRINTING INK SERICOL LTD (GB) 2016-03-02 EP disclosed
EP-2041230-B1 A PRINTING INK SERICOL LTD (GB) 2010-09-01 EP disclosed