Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30244540 | 1.00 | CA12 (0.46) | CA12CA1CA9CA2CA14 | |
| SCHEMBL30325035 | 0.87 | MAPT (0.58) | CA12CA1CA9MAPTPSMD10 | |
| SCHEMBL13252835 | 0.87 | MAPT (0.58) | CA12CA1CA9MAPTPSMD10 | |
| SCHEMBL30325226 | 0.87 | MAPT (0.58) | CA12CA1CA9MAPTPSMD10 | |
| SCHEMBL22032136 | 0.86 | CA12 (0.44) | CA12CA1CA9CA2CA14 | |
| SCHEMBL13873578 | 0.86 | GAA (0.54) | CA12CA1CA9CA2MAPT | |
| SCHEMBL26938534 | 0.84 | POLB (0.47) | CA12CA1CA9CA2STAT3 | |
| SCHEMBL29084498 | 0.83 | MAPT (0.63) | CA12CA1CA9MAPTPSMD10 | |
| SCHEMBL2386879 | 0.81 | CA12 (0.49) | CA12CA1CA9MAPTPSMD10 | |
| SCHEMBL1595317 | 0.81 | CA12 (0.45) | CA12CA1CA9CA2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251588-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2022-12-01 | — | — | WO | disclosed |