SCHEMBL2386879

SCHEMBL2386879

Cc1ccc(S(=O)(=O)OCCOc2ccc(C(=O)C(C)(C)O)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA9 Q16790 1/20 0.49
NPC1 O15118 3/20 0.43
STAT3 P40763 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.40
HRH2 P25021 1/20 0.40
HRH1 P35367 1/20 0.40
MAPT P10636 2/20 0.39
PSMD10 O75832 1/20 0.39
ENPP1 P22413 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23616751 0.88 NPC1 (0.41) CA12CA1CA9NPC1L3MBTL1
SCHEMBL11111198 0.84 STAT3 (0.59) CA12CA1CA9NPC1STAT3
SCHEMBL8069545 0.84 CA12 (0.63) CA12CA1CA9L3MBTL1POLB
SCHEMBL29084498 0.82 MAPT (0.63) CA12CA1CA9NPC1STAT3
SCHEMBL8675724 0.81 L3MBTL1 (0.44) L3MBTL1POLBHRH2HRH1MAPT
SCHEMBL2468529 0.81 MAPT (0.45) NPC1L3MBTL1MAPTALDH1A1PPARA
SCHEMBL30244540 0.81 CA12 (0.46) CA12CA1CA9NPC1STAT3
SCHEMBL30244725 0.81 CA12 (0.46) CA12CA1CA9NPC1STAT3
SCHEMBL19706188 0.81 CA12 (0.50) CA12CA1CA9L3MBTL1POLB
SCHEMBL30325035 0.79 MAPT (0.58) CA12CA1CA9NPC1STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464490-B1 PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA NV (BE) 2021-07-07 EP disclosed
US-10851254-B2 Photoinitiators and curable compositions AGFA NV (BE) 2020-12-01 US disclosed
US-20190144696-A1 PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA NV (BE) 2019-05-16 US disclosed
WO-2017211587-A1 PHOTOINITIATORS AND CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2017-12-14 WO disclosed
US-8492452-B2 Polymerizable photoinitiators and radiation curable compositions AGFA GRAPHICS NV (BE) 2013-07-23 US disclosed
US-8492452-B2 Polymerizable photoinitiators and radiation curable compositions AGFA GRAPHICS NV (BE) 2013-07-23 US disclosed
US-8492452-B2 Polymerizable photoinitiators and radiation curable compositions AGFA GRAPHICS NV (BE) 2013-07-23 US disclosed
US-20110224324-A1 POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-09-15 US disclosed
US-20110224324-A1 POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-09-15 US disclosed
US-20110224324-A1 POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2011-09-15 US disclosed
WO-2010069758-A1 POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS AGFA GRAPHICS NV (BE) 2010-06-24 WO disclosed
EP-2199273-A1 Polymerizable photoinitiators and radiation curable compositions AGFA Graphics NV (BE) 2010-06-23 EP disclosed
EP-2053102-A1 Radiation curable inkjet fluids and inks improved for photoyellowing Agfa Graphics N.V. (BE) 2009-04-29 EP disclosed
US-5837746-A Coreactive photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-17 US disclosed
US-5532112-A PHOTOPOLYMERIZATION CIBA-GEIGY CORPORATION (US) 1996-07-02 US disclosed
EP-0281941-B1 Coreactive photoinitiators CIBA GEIGY AG (CH) 1993-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224324-A1 POLYMERIZABLE PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS WEE1, ZYX, MTR CA12 1456/4885CA1 1609/4885CA9 1089/4885
US-20190144696-A1 PHOTOINITIATORS AND CURABLE COMPOSITIONS FLOT1, VIM, FLNA CA12 2308/4885CA1 4282/4885CA9 831/4885
US-10851254-B2 Photoinitiators and curable compositions FLOT1, VIM, FLNA CA12 2308/4885CA1 4282/4885CA9 831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.