Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30244782 | 1.00 | KMT2A (0.51) | KMT2AHTTTSHRNAAANPC1 | |
| SCHEMBL30378490 | 0.90 | L3MBTL1 (0.55) | KMT2AHTTTSHRNPC1MAPT | |
| SCHEMBL7643455 | 0.89 | KMT2A (0.61) | KMT2AHTTTSHRNPC1MAPT | |
| SCHEMBL30380288 | 0.86 | TSHR (0.48) | KMT2AHTTTSHRNAAANPC1 | |
| SCHEMBL27172785 | 0.83 | TSHR (0.45) | KMT2AHTTTSHRNAAATDP1 | |
| SCHEMBL26601450 | 0.81 | TSHR (0.52) | KMT2AHTTTSHRNAAANPC1 | |
| SCHEMBL19067473 | 0.81 | TSHR (0.44) | KMT2AHTTTSHRNAAANPC1 | |
| SCHEMBL4608747 | 0.80 | TSHR (0.74) | HTTTSHRNAAATDP1L3MBTL1 | |
| SCHEMBL9505432 | 0.80 | TSHR (0.74) | HTTTSHRNAAATDP1L3MBTL1 | |
| SCHEMBL10895400 | 0.80 | TSHR (0.74) | HTTTSHRNAAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251588-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2022-12-01 | — | — | WO | disclosed |