Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30244751 | 0.90 | KMT2A (0.51) | L3MBTL1TDP1KMT2AHTTTSHR | |
| SCHEMBL30244782 | 0.90 | KMT2A (0.51) | L3MBTL1TDP1KMT2AHTTTSHR | |
| SCHEMBL9223815 | 0.87 | L3MBTL1 (0.55) | L3MBTL1TDP1KMT2AHTTTSHR | |
| SCHEMBL8921201 | 0.87 | L3MBTL1 (0.55) | L3MBTL1TDP1KMT2AHTTTSHR | |
| SCHEMBL7643455 | 0.86 | KMT2A (0.61) | L3MBTL1TDP1KMT2AHTTTSHR | |
| SCHEMBL10600059 | 0.83 | PLA2G10 (0.46) | L3MBTL1TDP1KMT2AHTT | |
| SCHEMBL16829758 | 0.83 | TDP1 (0.50) | L3MBTL1TDP1KMT2AHTTTSHR | |
| SCHEMBL9011734 | 0.82 | TSHR (0.67) | L3MBTL1TDP1KMT2ATSHRHRH4 | |
| SCHEMBL9011646 | 0.82 | TSHR (0.67) | L3MBTL1TDP1KMT2ATSHRHRH4 | |
| SCHEMBL9011624 | 0.82 | TSHR (0.67) | L3MBTL1TDP1KMT2ATSHRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023056423-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR USE AS BIFUNCTIONAL DEGRADERS | ESSA PHARMA, INC. (CA) | 2023-04-06 | — | — | WO | disclosed |