Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245388 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL30245466 | 0.94 | ALDH1A1 (0.54) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL30245128 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL30245507 | 0.92 | ALDH1A1 (0.47) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL30245660 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL29194642 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL30245140 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL30245590 | 0.89 | ALDH1A1 (0.52) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL30245178 | 0.89 | ALDH1A1 (0.47) | ALDH1A1TSHRSMN1; SMN2NPSR1EPHX2 | |
| SCHEMBL25263709 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |