Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245588 | 0.95 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2NPSR1ABCB1 | |
| SCHEMBL30245750 | 0.94 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL25426334 | 0.94 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL30245388 | 0.94 | ALDH1A1 (0.58) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL30244883 | 0.93 | ALDH1A1 (0.49) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL25263709 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL30245558 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL30244907 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2NPSR1ABCB1 | |
| SCHEMBL30245373 | 0.89 | ALDH1A1 (0.53) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 | |
| SCHEMBL30244928 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TSHRSMN1; SMN2NPSR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |