SCHEMBL3024653

SCHEMBL3024653

CC(C)(C)P(=O)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.35
FDPS P14324 1/20 0.33
GRM4 Q14833 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3030314 0.80 PPARD (0.40) TSHRLMNAFDPSGRM4
SCHEMBL3026013 0.76 PPARD (0.32) TSHRGRM4
SCHEMBL3778435 0.73
SCHEMBL25518775 0.71 ALDH1A1 (0.37) TSHR
SCHEMBL14467302 0.69 HPGD (0.32) FDPSGRM4
Ethylene Glycol SCHEMBL5487531 0.67 LMNA (0.38) TSHRLMNAFDPSGRM4
SCHEMBL1085715 0.65
SCHEMBL335957 0.65
SCHEMBL8764191 0.63 LMNA (0.35) TSHRLMNAFDPSGRM4
1,4-Butanediol SCHEMBL5492105 0.63 SMN1; SMN2 (0.36) TSHRLMNAFDPSGRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490065-B1 Fire retardant epoxy resin compositions CYTEC TECH CORP (US) 1998-05-06 EP claimed
EP-0490065-A2 Fire retardant epoxy resin compositions CYTEC TECHNOLOGY CORP. (US) 1992-06-17 EP claimed
US-5084546-A Dihydroxymethyl phosphine oxide as a fire retardant AMERICAN CYANAMID COMPANY (US) 1992-01-28 US claimed
US-8084524-B2 Flame retardant combinations of hydroxyalkyl phosphine oxides with 1,3,5-triazines and epoxides BASF SE (DE) 2011-12-27 US disclosed
US-20100210763-A1 FLAME RETARDANT COMBINATIONS OF HYDROXYALKYL PHOSPHINE OXIDES WITH 1,3,5-TRIAZINES AND EPOXIDES BASF SE (DE) 2010-08-19 US disclosed
EP-2190914-A2 FLAME RETARDANT COMBINATIONS OF HYDROXYALKYL PHOSPHINE OXIDES WITH 1,3,5-TRIAZINES AND EPOXIDES BASF SE (DE) 2010-06-02 EP disclosed
WO-2009034023-A2 FLAME RETARDANT COMBINATIONS OF HYDROXYALKYL PHOSPHINE OXIDES WITH 1,3,5-TRIAZINES AND EPOXIDES BASF SE (CH) 2009-03-19 WO disclosed
EP-0490065-B1 Fire retardant epoxy resin compositions CYTEC TECH CORP (US) 1998-05-06 EP disclosed
EP-0490065-A2 Fire retardant epoxy resin compositions CYTEC TECHNOLOGY CORP. (US) 1992-06-17 EP disclosed
US-5084546-A Dihydroxymethyl phosphine oxide as a fire retardant AMERICAN CYANAMID COMPANY (US) 1992-01-28 US disclosed