Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570966 | 0.94 | ALDH1A1 (0.77) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| 2-Hydroxybenzoic Acid Hexyl Ester SCHEMBL29085497 | 0.92 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL7459965 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL1005991 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL1923016 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL411474 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4731100 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL8927962 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL2801630 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| 2-Hydroxybenzoic Acid Hexyl Ester SCHEMBL113059 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310072-A1 | ULTRAVIOLET ABSORBER, COMPOSITION, COSMETIC PRODUCT, AND PROCESS FOR PREPARING COSMETIC PRODUCT | MFCI (Huanggang) Co., Ltd. (CN) | 2024-01-24 | — | — | EP | claimed |
| EP-4310072-A1 | ULTRAVIOLET ABSORBER, COMPOSITION, COSMETIC PRODUCT, AND PROCESS FOR PREPARING COSMETIC PRODUCT | MFCI (Huanggang) Co., Ltd. (CN) | 2024-01-24 | — | — | EP | disclosed |
| US-20170105910-A1 | UV FILTER CAPSULE | BASF SE (DE) | 2017-04-20 | — | — | US | disclosed |
| US-20100209463-A1 | UV FILTER CAPSULE | MERCK PATENT GMBH (DE) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105910-A1 | UV FILTER CAPSULE | UROD, MITF, NISCH | ALDH1A1 801/4885TSHR 3400/4885LMNA 1490/4885 |
| US-20100209463-A1 | UV FILTER CAPSULE | UROD, MITF, NISCH | ALDH1A1 801/4885TSHR 3400/4885LMNA 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.