6Bio

6Bio

SCHEMBL30249771

O=C1Nc2cc(Br)ccc2/C1=C1/Nc2ccccc2/C1=N\O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.48
IDO1 P14902 2/20 0.42
TDO2 P48775 1/20 0.42
LRRK2 Q5S007 6/20 0.41
NTRK1 P04629 1/20 0.40
CCNA2 P20248 1/20 0.40
CDK2 P24941 1/20 0.40
CCNA1 P78396 1/20 0.40
TGM2 P21980 1/20 0.39
CES1 P23141 1/20 0.39
CCNB2 O95067 2/20 0.39
CDK1 P06493 2/20 0.39
CCNB1 P14635 2/20 0.39
CCNB3 Q8WWL7 2/20 0.39
RAF1 P04049 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
HSP90AA1 P07900 1/20 0.38
CCR6 P51684 1/20 0.38
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6Bio SCHEMBL21067440 1.00 AGTR1 (0.48) AGTR1IDO1TDO2LRRK2NTRK1
6Bio SCHEMBL14088703 1.00 AGTR1 (0.48) AGTR1IDO1TDO2LRRK2NTRK1
SCHEMBL22300057 1.00 AGTR1 (0.48) AGTR1IDO1TDO2LRRK2NTRK1
6Bio SCHEMBL470802 1.00 AGTR1 (0.48) AGTR1IDO1TDO2LRRK2NTRK1
6Bio SCHEMBL4997980 1.00 AGTR1 (0.48) AGTR1IDO1TDO2LRRK2NTRK1
6Bio SCHEMBL29975657 0.99 AGTR1 (0.47) AGTR1IDO1TDO2LRRK2NTRK1
6Bio SCHEMBL27160645 0.99 AGTR1 (0.47) AGTR1IDO1TDO2LRRK2NTRK1
Indirubin 2 SCHEMBL22215161 0.91 AGTR1 (0.49) AGTR1IDO1TDO2LRRK2NTRK1
Indirubin 2 SCHEMBL30380962 0.91 AGTR1 (0.49) AGTR1IDO1TDO2LRRK2NTRK1
SCHEMBL3850179 0.91 LRRK2 (0.50) AGTR1IDO1TDO2LRRK2NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689063-A1 COMPOSITIONS AND METHODS FOR DIFFERENTIATING RPE CELLS Stemcell Technologies Canada Inc. (CA) 2026-02-11 EP disclosed
WO-2025135136-A1 METHOD FOR PRODUCING NAIL MATRIX CELLS 学校法人関西医科大学 2025-06-26 WO disclosed
WO-2025127102-A1 METHOD FOR PRODUCING HEPATIC STEM CELLS 学校法人関西医科大学 2025-06-19 WO disclosed
WO-2024207102-A1 COMPOSITIONS AND METHODS FOR DIFFERENTIATING RPE CELLS STEMCELL TECHNOLOGIES CANADA INC. (CA) 2024-10-10 WO disclosed
EP-3681504-B1 METHODS OF DETECTION USING X-RAY FLUORESCENCE ICAGEN INC (US) 2023-08-23 EP disclosed
US-11573224-B2 Methods of detection using X-ray fluorescence ICAGEN, LLC (US) 2023-02-07 US disclosed