Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22300057 | 0.99 | AGTR1 (0.48) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| 6Bio SCHEMBL21067440 | 0.99 | AGTR1 (0.48) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| 6Bio SCHEMBL14088703 | 0.99 | AGTR1 (0.48) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| 6Bio SCHEMBL470802 | 0.99 | AGTR1 (0.48) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| 6Bio SCHEMBL4997980 | 0.99 | AGTR1 (0.48) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| 6Bio SCHEMBL30249771 | 0.99 | AGTR1 (0.48) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| 6Bio SCHEMBL27160645 | 0.98 | AGTR1 (0.47) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| Indirubin 2 SCHEMBL22215161 | 0.90 | AGTR1 (0.49) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| Indirubin 2 SCHEMBL30380962 | 0.90 | AGTR1 (0.49) | AGTR1IDO1TDO2LRRK2NTRK1 | |
| SCHEMBL3850179 | 0.90 | LRRK2 (0.50) | AGTR1IDO1TDO2LRRK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228467-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENT RESEARCH (IN) | 2024-07-11 | — | — | US | claimed |
| US-20240228467-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENT RESEARCH (IN) | 2024-07-11 | — | — | US | disclosed |
| EP-4329748-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022229986-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2022-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228467-A1 | INDIRUBIN COMPOUNDS AND METHODS THEREOF | ATG7, SQSTM1, BECN1 | AGTR1 4746/4885IDO1 66/4885TDO2 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.