Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360975 | 0.83 | ATM (0.41) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL28395559 | 0.79 | ATM (0.43) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL28361039 | 0.78 | GNAI3 (0.41) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL28366947 | 0.78 | ATM (0.85) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL10722542 | 0.78 | ATM (0.85) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL19574089 | 0.78 | ATM (0.95) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL27487132 | 0.78 | ATM (0.85) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL13655626 | 0.77 | ATM (0.45) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL28360951 | 0.77 | GNAI3 (0.43) | ATMKMT2AL3MBTL1MEN1TDP1 | |
| SCHEMBL28364611 | 0.77 | GNAI3 (0.43) | ATMKMT2AL3MBTL1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109152933-B | Compounds that induce degradation of anti-apoptotic BCL-2 family proteins and uses thereof | 生物风险投资有限责任公司 | 2022-12-02 | — | — | CN | disclosed |