Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28361039 | 0.95 | GNAI3 (0.41) | ATMGNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL28360951 | 0.94 | GNAI3 (0.43) | ATMGNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL28364611 | 0.94 | GNAI3 (0.43) | ATMGNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL28364487 | 0.94 | GNAI3 (0.43) | ATMGNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL28360880 | 0.90 | CA2 (0.38) | ATMGNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL30250011 | 0.83 | ATM (0.59) | ATML3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL29969222 | 0.81 | CA2 (0.39) | DDB1CRBNCA2CA12CA1 | |
| SCHEMBL15648204 | 0.80 | TPSAB1 (0.34) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL16756662 | 0.78 | GNAI3 (0.56) | ATMGNAI3GNAO1GNAI1ITGB3 | |
| SCHEMBL9415769 | 0.78 | GNAI3 (0.56) | ATMGNAI3GNAO1GNAI1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845445-A | Connecting body, preparation method and application thereof, and thalidomide-based PROTACs intermediate and application thereof | 苏州爱玛特生物科技有限公司 | 2020-02-28 | — | — | CN | disclosed |