Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALPL | P05186 | 5/20 | 0.59 |
| ▸ | ALPI | P09923 | 5/20 | 0.59 |
| ▸ | ALPG | P10696 | 4/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30250253 | 0.94 | KMT2A (0.55) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL30250048 | 0.90 | KMT2A (0.62) | KMT2AALPLALPIALPGKDM4E | |
| SCHEMBL30250144 | 0.89 | KDM4E (0.53) | KMT2AKDM4EALDH1A1TDP1SSTR5 | |
| SCHEMBL30250001 | 0.86 | ALPL (0.63) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL30250097 | 0.84 | KMT2A (0.68) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL30250070 | 0.76 | KDM4E (0.66) | KMT2AKDM4EALDH1A1TDP1SSTR5 | |
| SCHEMBL2423206 | 0.72 | SSTR5 (0.58) | KDM4EALDH1A1SSTR5 | |
| SCHEMBL3570256 | 0.72 | SSTR5 (0.86) | SSTR5 | |
| SCHEMBL28778465 | 0.72 | SMN1; SMN2 (0.61) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL29087391 | 0.71 | KDM4E (0.68) | KMT2AKDM4EALDH1A1TDP1SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387735-A2 | ANTIVIRAL DRUGS TARGETING THE N-TERMINAL DOMAIN (NTD) OF THE CORONAVIRUS SPIKE RECEPTOR BINDING DOMAIN (RBD) | SOUTHWEST RESEARCH INSTITUTE (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023039330-A2 | ANTIVIRAL DRUGS TARGETING THE N-TERMINAL DOMAIN (NTD) OF THE CORONAVIRUS SPIKE RECEPTOR BINDING DOMAIN (RBD) | SOUTHWEST RESEARCH INSTITUTE (US) | 2023-03-16 | — | — | WO | disclosed |