Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | ALPL | P05186 | 5/20 | 0.67 |
| ▸ | ALPI | P09923 | 5/20 | 0.67 |
| ▸ | ALPG | P10696 | 4/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30250001 | 0.85 | ALPL (0.63) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL30250100 | 0.84 | KMT2A (0.62) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL30250253 | 0.77 | KMT2A (0.55) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL28778465 | 0.76 | SMN1; SMN2 (0.61) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL26082691 | 0.75 | ACKR3 (0.59) | KMT2AACKR3 | |
| SCHEMBL8094101 | 0.75 | POLB (0.65) | KMT2AACKR3 | |
| SCHEMBL30473391 | 0.74 | KMT2A (0.53) | KMT2AALPLALPIALPGABL1 | |
| SCHEMBL23109077 | 0.74 | MGLL (0.64) | KMT2AALPLALPIALPGMGLL | |
| SCHEMBL17270257 | 0.73 | ACKR3 (0.78) | ACKR3 | |
| SCHEMBL4172844 | 0.72 | LTA4H (0.65) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387735-A2 | ANTIVIRAL DRUGS TARGETING THE N-TERMINAL DOMAIN (NTD) OF THE CORONAVIRUS SPIKE RECEPTOR BINDING DOMAIN (RBD) | SOUTHWEST RESEARCH INSTITUTE (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023039330-A2 | ANTIVIRAL DRUGS TARGETING THE N-TERMINAL DOMAIN (NTD) OF THE CORONAVIRUS SPIKE RECEPTOR BINDING DOMAIN (RBD) | SOUTHWEST RESEARCH INSTITUTE (US) | 2023-03-16 | — | — | WO | disclosed |