Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20911188 | 0.77 | KDM4E (0.47) | RAB9AHSP90AA1ADORA2AADORA1PDPK1 | |
| SCHEMBL8936053 | 0.76 | KDM4E (0.47) | RAB9AHSP90AA1KDM4EALDH1A1GAA | |
| SCHEMBL452340 | 0.75 | KDM4E (0.57) | RAB9AHSP90AA1PDPK1KDM4EALDH1A1 | |
| Fluoride SCHEMBL27903468 | 0.74 | KDM4E (0.55) | RAB9AHSP90AA1PDPK1KDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28442530 | 0.74 | KDM4E (0.55) | RAB9AHSP90AA1PDPK1KDM4EALDH1A1 | |
| SCHEMBL3290082 | 0.73 | PDPK1 (0.43) | RAB9AADORA2AADORA1PDPK1KDM4E | |
| SCHEMBL28554182 | 0.71 | KDM4E (0.49) | RAB9AHSP90AA1KDM4EALDH1A1GAA | |
| SCHEMBL2651653 | 0.71 | KDM4E (0.48) | RAB9AHSP90AA1KDM4EALDH1A1GAA | |
| SCHEMBL29741178 | 0.71 | KDM4E (0.48) | RAB9AHSP90AA1KDM4EALDH1A1GAA | |
| SCHEMBL4902877 | 0.70 | RAB9A (0.61) | RAB9AHSP90AA1PDPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651358-B | 4-aminopyridine derivative, pharmaceutical composition, preparation method and application thereof | 上海迪诺医药科技有限公司 | 2023-04-07 | — | — | CN | disclosed |