Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25549352 | 1.00 | KLKB1 (0.42) | KLKB1CFDPOLBCASP6CTDSP1 | |
| SCHEMBL25249527 | 1.00 | KLKB1 (0.42) | KLKB1CFDPOLBCASP6CTDSP1 | |
| SCHEMBL19234672 | 0.80 | CFD (0.45) | KLKB1CFD | |
| SCHEMBL29840887 | 0.80 | CFD (0.45) | KLKB1CFD | |
| SCHEMBL18576410 | 0.80 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| SCHEMBL17034800 | 0.80 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| SCHEMBL19234185 | 0.80 | CFD (0.45) | KLKB1CFD | |
| SCHEMBL18572911 | 0.80 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17023486 | 0.79 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18548455 | 0.79 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |