Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25249527 | 1.00 | KLKB1 (0.42) | KLKB1CFDPOLBCASP6CTDSP1 | |
| SCHEMBL30254296 | 1.00 | KLKB1 (0.42) | KLKB1CFDPOLBCASP6CTDSP1 | |
| SCHEMBL19234672 | 0.80 | CFD (0.45) | KLKB1CFD | |
| SCHEMBL29840887 | 0.80 | CFD (0.45) | KLKB1CFD | |
| SCHEMBL18576410 | 0.80 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| SCHEMBL17034800 | 0.80 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| SCHEMBL19234185 | 0.80 | CFD (0.45) | KLKB1CFD | |
| SCHEMBL18572911 | 0.80 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17023486 | 0.79 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18548455 | 0.79 | CFD (0.40) | KLKB1CFDPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | C5, C9, C1QBP | KLKB1 737/4885CFD 14/4885POLB 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.