Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885406 | 1.00 | CA2 (0.39) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL3220102 | 0.85 | CA2 (0.38) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL30254317 | 0.83 | SMN1; SMN2 (0.43) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL31263190 | 0.83 | SMN1; SMN2 (0.37) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL23885689 | 0.83 | SMN1; SMN2 (0.43) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL23885291 | 0.83 | CA2 (0.41) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL30254414 | 0.83 | CA2 (0.41) | CA2SMN1; SMN2TP53MAPTJAK2 | |
| SCHEMBL3226137 | 0.83 | CYP1A2 (0.42) | SMN1; SMN2MAPTPDK1PDK2PDK3 | |
| SCHEMBL22632771 | 0.83 | L3MBTL1 (0.46) | SMN1; SMN2TP53MAPTHTTMEN1 | |
| SCHEMBL29414711 | 0.83 | L3MBTL1 (0.46) | SMN1; SMN2TP53MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |