Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25733434 | 1.00 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3R1HDAC3HDAC4 | |
| SCHEMBL25231922 | 0.90 | PIK3CD (0.44) | PIK3CDPIK3CAHDAC3HDAC4HDAC1 | |
| SCHEMBL25421195 | 0.87 | PIK3CD (0.40) | PIK3CDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25229681 | 0.85 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3R1HDAC3HDAC4 | |
| SCHEMBL31730923 | 0.84 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3R1HDAC3HDAC4 | |
| SCHEMBL25733410 | 0.84 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3R1HDAC3HDAC4 | |
| SCHEMBL25733559 | 0.84 | GPR119 (0.43) | PIK3CDPIK3CAHDAC3HDAC4HDAC1 | |
| SCHEMBL31730879 | 0.84 | GPR119 (0.43) | PIK3CDPIK3CAHDAC3HDAC4HDAC1 | |
| SCHEMBL30254686 | 0.83 | KDM4E (0.38) | PIK3CDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25733452 | 0.83 | KDM4E (0.38) | PIK3CDHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4444312-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-4161519-A1 | PURINES AND METHODS OF THEIR USE | Yumanity Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |