Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.52 |
| ▸ | APLNR | P35414 | 3/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | RAMP3 | O60896 | 7/20 | 0.47 |
| ▸ | CALCR | P30988 | 7/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29608303 | 0.89 | C5AR1 (0.55) | C5AR1APLNRMC4RRAMP3CALCR | |
| SCHEMBL29606806 | 0.89 | C5AR1 (0.54) | C5AR1APLNRMC4RRAMP3CALCR | |
| SCHEMBL29607837 | 0.88 | APLNR (0.49) | C5AR1APLNRRAMP3CALCRPLK1 | |
| SCHEMBL30262021 | 0.87 | APLNR (0.57) | C5AR1APLNRMC4RRAMP3CALCR | |
| SCHEMBL30198795 | 0.86 | CTSL (0.48) | C5AR1APLNRMC4RRAMP3CALCR | |
| SCHEMBL29608116 | 0.86 | C5AR1 (0.57) | C5AR1APLNRMC4RPLK1 | |
| SCHEMBL29608024 | 0.86 | C5AR1 (0.57) | C5AR1APLNRMC4RPLK1 | |
| SCHEMBL29607839 | 0.85 | C5AR1 (0.56) | C5AR1APLNRMC4RPLK1 | |
| SCHEMBL29607016 | 0.85 | C5AR1 (0.56) | C5AR1APLNRPLK1 | |
| SCHEMBL31182755 | 0.85 | CALCR (0.60) | APLNRRAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250134958-A1 | PHARMACEUTICAL FORMULATIONS AND METHODS OF MAKING THE SAME | AMGEN INC. | 2025-05-01 | — | — | US | disclosed |
| US-12214013-B2 | Methods of treatment of arthritis and/or psoriasis with pharmaceutical formulations of etanercept | AMGEN INC. (US) | 2025-02-04 | — | — | US | disclosed |
| US-20230080571-A1 | PHARMACEUTICAL FORMULATIONS AND METHODS OF MAKING THE SAME | AMGEN INC. | 2023-03-16 | — | — | US | disclosed |