Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547008 | 0.77 | ALDH1A1 (0.36) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7547003 | 0.77 | ALDH1A1 (0.36) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7546297 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19332329 | 0.70 | MEN1 (0.35) | MAPTSMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL29079127 | 0.70 | MEN1 (0.35) | MAPTSMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL26617736 | 0.68 | MAPT (0.33) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL26617731 | 0.68 | MAPT (0.33) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL17887331 | 0.67 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL24185565 | 0.65 | MEN1 (0.33) | MAPTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL2730136 | 0.65 | MEN1 (0.33) | MAPTKMT2AMEN1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4402126-A1 | AHR AGONISTS | Eli Lilly and Company (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-118215654-A | AHR agonists | 伊莱利利公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2023039278-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2023-03-16 | — | — | WO | disclosed |