Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.53 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.53 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 4/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30379291 | 0.80 | PIP4K2A (0.51) | MAPK1MEN1KMT2AGAAPIP4K2C | |
| SCHEMBL4184328 | 0.78 | PLK4 (0.61) | FGFR1MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL29997075 | 0.73 | AURKA (0.62) | AURKAAURKB | |
| SCHEMBL30353143 | 0.73 | MEN1 (0.51) | FGFR1MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL16363312 | 0.72 | FGFR1 (0.79) | MAPK1FGFR1MEN1KMT2AGAA | |
| SCHEMBL7253942 | 0.72 | MAPK1 (0.59) | MAPK1FGFR1MEN1KMT2AGAA | |
| SCHEMBL30353126 | 0.72 | MEN1 (0.50) | FGFR1MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL24197138 | 0.71 | RAB9A (0.57) | MAPK1FGFR1MEN1KMT2AGAA | |
| SCHEMBL30353167 | 0.71 | MEN1 (0.56) | FGFR1MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL166340 | 0.70 | NTRK1 (0.45) | AURKAAURKBPLK4PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043863-A1 | HETEROAROMATIC DERIVATIVES FOR USE AS REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | WEE2, WEE1, RORB | MAPK1 225/4885FGFR1 916/4885MEN1 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.