Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302825 | 1.00 | KMT2A (0.42) | KMT2AMEN1KDM4ECXCR2NPC1 | |
| SCHEMBL25302964 | 0.83 | MEN1 (0.45) | KMT2AMEN1KDM4ECXCR2NPC1 | |
| SCHEMBL30198344 | 0.83 | MEN1 (0.45) | KMT2AMEN1KDM4ECXCR2NPC1 | |
| SCHEMBL23925436 | 0.78 | MEN1 (0.52) | KMT2AMEN1KDM4ECXCR2CYP3A4 | |
| SCHEMBL30198468 | 0.78 | MEN1 (0.52) | KMT2AMEN1KDM4ECXCR2CYP3A4 | |
| SCHEMBL26631548 | 0.73 | KMT2A (0.40) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL30139037 | 0.73 | KMT2A (0.40) | KMT2AMEN1LMNAMAPTMAPK1 | |
| SCHEMBL5789975 | 0.72 | MEN1 (0.46) | KMT2AMEN1KDM4ECXCR2CYP3A4 | |
| SCHEMBL10870059 | 0.71 | MEN1 (0.50) | KMT2AMEN1KDM4ECXCR2NPC1 | |
| SCHEMBL27649932 | 0.70 | SLC6A3 (0.57) | KMT2AMEN1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443268-A | Benzimidazole derivatives | 豪夫迈·罗氏有限公司 | 2022-12-06 | — | — | CN | disclosed |