SCHEMBL30258766

SCHEMBL30258766

CCc1oc2c(C)cccc2c1C(=O)c1cc(I)c(O)c(I)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 8/20 0.68
▸ EYA3 Q99504 7/20 0.67
▸ MEN1 O00255 2/20 0.67
▸ ABCB11 O95342 2/20 0.67
▸ LMNA P02545 2/20 0.67
▸ PGR P06401 2/20 0.67
▸ ADRA2A P08913 2/20 0.67
▸ TBXA2R P21731 2/20 0.67
▸ OPRM1 P35372 2/20 0.67
▸ SLC6A3 Q01959 2/20 0.67
▸ KMT2A Q03164 2/20 0.67
▸ BIRC5 O15392 1/20 0.67
▸ HTR1A P08908 1/20 0.67
▸ DRD1 P21728 1/20 0.67
▸ PTGS1 P23219 1/20 0.67
▸ SLC6A2 P23975 1/20 0.67
▸ PDE4A P27815 1/20 0.67
▸ ADORA1 P30542 1/20 0.67
▸ DRD3 P35462 1/20 0.67
▸ HRH3 Q9Y5N1 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25391820 0.88 EYA3 (0.70) TTREYA3MEN1ABCB11LMNA
SCHEMBL30258571 0.88 TTR (0.72) TTREYA3MEN1ABCB11LMNA
SCHEMBL30258897 0.86 TTR (0.69) TTREYA3MEN1ABCB11LMNA
SCHEMBL30258456 0.86 SLC22A12 (0.68) TTREYA3MEN1ABCB11LMNA
Benziodarone SCHEMBL31326233 0.81 EYA3 (1.00) TTREYA3MEN1ABCB11LMNA
Benziodarone SCHEMBL308541 0.81 EYA3 (1.00) TTREYA3MEN1ABCB11LMNA
SCHEMBL26809506 0.77 SLC22A12 (0.62) TTREYA3MEN1ABCB11LMNA
SCHEMBL25393151 0.77 TTR (0.55) TTREYA3MEN1ABCB11LMNA
SCHEMBL25391545 0.76 EYA3 (0.70) TTREYA3MEN1ABCB11LMNA
SCHEMBL30258719 0.76 TTR (0.79) TTREYA3MEN1ABCB11LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282741-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF INNOVO THERAPEUTICS INC. (KR) 2025-09-11 — — US claimed
EP-4413981-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Innovo Therapeutics Inc. (KR) 2024-08-14 — — EP claimed
CN-118043043-A Benzofuranyl hydroxy phenyl ketone derivative compound or pharmaceutically acceptable salt thereof 因诺沃治疗有限公司 2024-05-14 — — CN claimed
WO-2023059121-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF (주)이노보테라퓨틱스 2023-04-13 — — WO claimed
US-20250282741-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF INNOVO THERAPEUTICS INC. (KR) 2025-09-11 — — US disclosed
EP-4413981-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Innovo Therapeutics Inc. (KR) 2024-08-14 — — EP disclosed
CN-118043043-A Benzofuranyl hydroxy phenyl ketone derivative compound or pharmaceutically acceptable salt thereof 因诺沃治疗有限公司 2024-05-14 — — CN disclosed
WO-2023059121-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF (주)이노보테라퓨틱스 2023-04-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282741-A1 NOVEL BENZOFURANYL HYDROXYPHENYL METHANONE DERIVATIVE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF HSPH1, HSP90AA1, HSPD1 TTR 1428/4885EYA3 1904/4885MEN1 2760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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